Lyantonde District is a district in southern Central Uganda. It is named after the 'chief town' of the district, Lyantonde, where the district headquarters are located. It is bordered by Sembabule District to the north and northeast, Lwengo District to the east, Rakai District to the south, and Kiruhura District to the west. The 'chief town' of the district, Lyantonde, is located approximately 78 kilometres (48 mi), by road, west of the city of Masaka, the largest metropolitan area in the sub-region. The coordinates of the district are: 00 25S, 31 10E.